Harpoon Therapeutics to Present Interim Clinical Data for TriTAC® HPN424 at the ASCO20 Virtual Scientific Program
Full details of the presentation are as follows:
Abstract/Poster Title: First-in-human, Phase 1 study of HPN424, a tri-specific half-life extended PSMA-targeting T cell engager, in patients with metastatic castration-resistant prostate cancer (mCRPC)
Authors:
Session: Genitourinary Cancer – Prostate, Testicular, and Penile
Date and Time:
Abstract / Poster Number: 5552 / 133
Location:
A copy of the presentation will be available on the company’s website at https://ir.harpoontx.com/events-and-presentations.
Conference Call and Webcast
Harpoon’s management will host a webcast and conference call at
877-407-9716 for domestic callers
201-493-6779 for international callers
A live webcast of the call will be available from the Events and Presentations section of the company’s website at https://ir.harpoontx.com/events-and-presentations and will be archived there shortly after the live event.
About the Phase 1 Clinical Trial for HPN424
This Phase 1 trial is a multicenter, open-label study designed to evaluate the safety, tolerability, pharmacokinetics and activity of HPN424 in patients with mCRPC who are progressing. The trial is titled, “A Phase 1 Open-label, Multicenter, Dose Escalation and Dose Expansion Study of the Safety, Tolerability, and Pharmacokinetics of HPN424 in Patients with Advanced Prostate Cancer Refractory to Androgen Therapy.” For additional information about the trial, please visit www.clinicaltrials.gov using the identifier NCT03577028.
The initial phase of the trial is a dose escalation phase, with the goal of determining a recommended dose for the expansion phase of the trial. HPN424 is being administered to patients once weekly by intravenous infusion. The primary outcome measures are an assessment of safety and tolerability, pharmacokinetics, and determination of a dose for the expansion phase of the trial. Secondary endpoints include overall response rate, progression free and overall survival, and duration of response. The expansion portion of the trial will further evaluate the safety and activity of HPN424 in patients with mCRPC.
About
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Contacts:
Chief Financial Officer
650-443-7400
media@harpoontx.com
Westwicke ICR
Managing Director
858-356-5932
robert.uhl@westwicke.com
Source: Harpoon Therapeutics